Cleveland Research Team Identifies Biological Mechanism That May Explain Obesity Relapse

• New research explains why weight regain is common after dieting or stopping GLP-1 medications.

• Researchers discovered that obesity creates a lasting "memory" in fat cells that keeps hunger signals elevated even after weight loss.

• Obesity “memory” can be passed from mother to child before birth.

• Blocking the asprosin pathway prevented weight regain and inherited obesity risk.